Ph.D. Program in Molecular Biology and Genetics

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Ph.D. Program in Molecular Biology and Genetics

  • Program tanımları
    Head of Department: Koyas Bilge

    Professors: Nazli Basak, Nes'e Bilgin, Koyas Bilge, Hande Caglayan, Cemile Erten*, Ahmet Koman, Aslihan Tolun

    Associate Professors: Ender Altiok*, Muge Turet Sayar, Nesrin Ozoren

    Assistant Professors: Esra Battaloglu, Necla Birgul-Iyison, Arzu Celik

    Instructor: Sahru Yuksel
    *Part-time


    DOCTOR OF PHILOSOPHY PROGRAM

    The Ph.D. program in Molecular Biology and Genetics consists of a minimum 7 courses and 21 credits, and a Ph. D. thesis.

    The required courses are:

    BIO 601 Advanced Techniques in Molecular Biology 3
    BIO 602 Advanced Techniques in Human Genetics 3

    Graduate Courses


    BIO 500 Modern Techniques in Molecular Biology
    BIO 501 Advanced Molecular Biology
    BIO 504 Medical Biochemistry
    BIO 506 Human Genetics
    BIO 510 Biochemistry of Nucleic Acids
    BIO 511 Advanced Genetics
    BIO 513 Biotechnology
    BIO 520 Laboratory Projects in Biology
    BIO 522 Modern Concepts in Biochemistry
    BIO 528 Immunology
    BIO 529 Developmental Biology
    BIO 560 Neurobiology
    BIO 579 Graduate Seminar
    BIO 581-583 Seminar
    BIO 580-599 Special Topics in Molecular Biology and Genetics
    BIO 601 Advanced Techniques in Molecular Biology
    BIO 602 Advanced Techniques in Human Genetics
    BIO 603 Research Methods in Molecular Biology
    BIO 605 Medical Genetics
    BIO 606 Biological Signal Transduction
    BIO 610 Plant Tissue Cultures for Biotechnology
    BIO 680-698 Advanced Topics in Molecular Biology and Genetics
    BIO 690 M.S. Thesis


    COURSE DESCRIPTIONS

    BIO 500 Modern Techniques in Molecular Biology (1+0+4) 3
    (Molekuler Biyolojide Guncel Teknikler)
    An independent research project under the supervision of a faculty member, through which students gain experience in advanced molecular biology techniques.

    BIO 501 Advanced Molecular Biology (Ileri Molekuler Biyoloji) (3+0+0) 3
    An extensive study of advanced topics related to prokaryotic and eukaryotic gene structure and regulation of gene expression, with special emphasis on experimental approaches such as recombiant DNA techniques, cloning vectors, preparation of cDNA and genomic libraries, clone selection and characterization, promoter/enhancer tests.

    BIO 504 Medical Biochemistry (Tibbi Biyokimya) (3+0+0) 3
    Use of biochemistry in etiology, diagnosis and treatment of disease; metabolic disorders, hormonal disorders; chemotherapy; immunotherapy.

    BIO 506 Human Genetics (Insan Genetigi) (3+0+0) 3
    Structure and organization of human chromosomes; chromosomal aberrations; diagnosis of genetic diseases; genetic counseling.

    BIO 510 Biochemistry of Nucleic Acids (Nukleik Asit Biyokimyasi) (3+0+0) 3
    Structure and function of nucleic acids; techniques used in their study; biosynthetic pathways for nucleic acid production.

    BIO 511 Advanced Genetics (Ileri Genetik) (3+0+0) 3
    Advanced study of molecular genetics; bacterial genetics; recombination; mammalian somatic cell genetics; developmental genetics; immunogenetics.

    BIO 513 Biotechnology (Biyoteknoloji) (3+0+0) 3
    Use of biological systems in medicine, industry and agriculture; food and drug production; industrial application of genetic engineering.

    BIO 520 Laboratory Projects in Biology (1+0+4) 3
    (Biyolojide Laboratuvar Projeleri)
    Introduction to biological research through an independent, original project under the supervision of a faculty member, in order to provide hands-on experience with the advanced techniques of molecular biology.

    BIO 522 Modern Concepts in Biochemistry (3+0+0) 3
    (Biyokimyada Guncel Kavramlar)
    Recent advances in biochemistry; structure, function and metabolism of macromolecules; biochemistry of cancer; mechanisms of action of anticancer agents.

    BIO 528 Immunology (Immunoloji) (3+0+0) 3
    Immunochemistry; structure of immunoglobulin molecules; antigen-antibody interactions; humoral and cellular immune responses.

    BIO 529 Developmental Biology (Gelisim Biyolojisi) (3+0+0) 3
    Fundamentals of developmental biology including fertilization, cleavage, gastrulation, neurulation, induction, determination, differentiation, pattern formation, teratology and sex determination.

    BIO 560 Neurobiology (Norobiyoloji) (3+0+0) 3
    Neuronal organization; rules of formation, maintenance and alterations of neuronal connections; mechanisms of neuronal signaling; integration and transformation of information by nerve cells.

    BIO 579 Graduate Seminar (Lisansustu Seminer) (0+1+0) 0 P/F
    Widening of students' perspectives and awareness of topics of interest to molecular biologists through seminars offered by faculty, guest speakers and graduate students.

    BIO 581-583 Seminar (Seminer) (1+0+4) 3
    Literature survey, preparation and presentation of seminars by the students on recent research topics in the field of molecular biology.

    BIO 580-599 Special Topics in Molecular Biology and Genetics (3+0+0) 3
    (Molekuler Biyoloji ve Genetikte Ozel Konular)
    Critical analysis of selected literature to study the recent advances in the field of specialization of the instructor.

    BIO 601 Advanced Techniques in Molecular Biology (1+0+4) 3
    (Molekuler Biyolojide Kullanilan Ileri Yontemler)
    Use of laboratory techniques in molecular biology through a supervised independent research project. The research topic and the special techniques are selected to facilitate development of a doctoral thesis project.

    BIO 602 Advanced Techniques in Human Genetics (1+0+4) 3
    (Insan Genetiginde Kullanilan Ileri Teknikler)
    Use of laboratory techniques in human genetics through a supervised independent research project. The research topic and the special techniques are selected to facilitate development of a doctoral thesis project.

    BIO 603 Research Methods in Molecular Biology (3+0+0) 3
    (Molekuler Biyolojide Arastirma Yontemleri)
    An extensive literature survey on a selected topic in molecular biology, presentation of a seminar and discussion of future research directions.

    BIO 605 Medical Genetics (Tibbi Genetik) (3+0+0) 3
    Patterns of single gene inheritance; genetic variation; the human genome; clinical cyto-genetics; sex chromosomes; genetics of the immune system; multifactorial inheritance; genetics of cancer; gene therapy; genetic counseling; prenatal diagnosis.

    BIO 606 Biological Signal Transduction (Biyolojik Sinyal Iletimi) (3+0+0) 3
    Cell-cell communication; classical and novel signaling pathways; cell surface and intracellular receptors; second messenger pathways.

    BIO 610 Plant Tissue Cultures for Biotechnology (3+0+0) 3
    (Bioteknolojide Bitki Doku Kulturu)
    Plant hormones, tissue culture techniques, somatic embryogenesis, use of genetically engineered crop plants in breeding.

    BIO 680-698 Advanced Topics in Molecular Biology and Genetics (3+0+0) 3
    (Molekuler Biyoloji ve Genetikte Ileri Konular)
    Offered by the faculty member in his/her own field of specialization and involve critical discussion of selected literature to study the recent advances.

    BIO 790 Ph.D. Thesis (Doktora Tezi)

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