Program tanımları
Biochemical Pharmacology and Toxicology
Involved Faculty Members :
Prof. Dr. Emel Arınç
Prof. Dr. Mesude İşcan
Prof. Dr. Tülin Güray
Prof. Dr. Orhan Adalı
Admission conditions for the field : The students who apply to this program are expected that they have taken the following courses or equivalents
BIO 307 Biochemistry I
BIO 308 Biochemistry II
BIO 353 Biochemistry
BIO 310 Biochemistry Laboratory
BIO 321 Bioanalytical Chemistry
BIO 425 Molecular Pharmacology
BIO 419 Biochemical Calculations
Ph.D.
BIO 600 Ph.D. Thesis
7 technical electives (List of suggested graduate courses)
BIO 522 Metabolic Aspects of Conjugation Reactions
BIO 520 Biometry
BIO 713 Molecular Aspects of Oxygenases
BCH 501 Free Radicals in Biochemical Systems
BCH 508 Biochemical Toxicology and Pharmacology
BIO 580 Controlled Release Systems and Drug Targeting
BIO 543 Experimental Enzymology
BIO 715 Genomics and Proteomics
BIO 512 Quantitative Problems in Biochemistry
BIO 503 Intermediary Metabolism and Regulation
Course Descriptions
BIO 600 Ph.D. Thesis NC
Program of research leading to Ph.D. degree, arranged between student a faculty member. Students registered to this course in all semesters starting from the beginning of their fifth semester while the research program or writing of thesis is in progress.
BIO 520 Biometry (2-2)3
The statistical techniques applicable in biological research. Emphasis will be given on the use of computers in biological sciences. Data in biology, descriptive statistic, elementary probability distributions, estimation and hypothesis testing, analysis of variance, regression, correlation and certain non-parametric tests are the topics covered. (Compulsory for Ph.D. students) (S/WE)*
BIO 522 Metabolic Aspects of Conjugation Reactions (3-0)3
Basic biochemical and molecular aspects of conjugation reactions and the conjugases. The glucuronidation, sulfation, acetylation, O-, N-, S- methylation, amino acid and glutathione conjugation reactions with emphasis on enzymological, metabolic, biological pharmacological and molecular biological concepts.(R)*
BIO 501 Seminar in Biology I (0-2)NC
Presentation of topics of general interest, current research activities and recent developments in biological sciences and related fields by graduate students, staff members and invited speakers.(F)*
BIO 580 Controlled Release Systems and Drug Targeting (3-0)3
Overview of the approaches to bioactive agent administration systems used in the targeting and delivery of biologically active materials and their fate in the body. Carriers such as liposomes, colloidal carriers, membranes, biodegradable systems, are to be covered. Approaches to genetic material delivery relevant with gene therapy and various anticancer, pain relief, antibiotic administration are discussed using current literature.
Prerequisite: Consent of the Instructor.
BIO 543 Experimental Enzymology (1-4)3
(See also BCH 543)
A laboratory course concerned with biochemical and molecular aspects of enzyme function. Purification and characterization of the enzymes, optimization of the enzyme assays, simple enzyme kinetics, spectrophotometry, SDs-polyacrylamide gel electrophoresis, enzyme linked immunosorbent assays (ELISA).(AF)*
BIO 715 Genomics and Proteomics (3-0)3
Concepts and current knowledge and applications in the rapidly emerging disciplines of structural and functional genomics (genome analysis and comparative genomics, technologies for transcriptional profiling, analysis of protein-protein interaction) and proteomics and related bioinformatics.
BIO 512 Quantitative Problems in Biochemistry (3-0)3
(See also BCH 512)
Solution of numerical problems in biochemistry involving acid-base chemistry, blood buffers, chemistry of biological molecules, enzymes, biochemical energetics, spectrophotometry, isotopes and scintillation counting.(R)*
503 Intermediary Metabolism and its Regulation (3-0)3
(See also BCH 503)
Intensive study of the metabolic pathways of carbohydrates, lipids and nitrogenous compounds and their interrelationships, including control mechanisms. The effects of hormonal and nutritional status on the activity of these major pathways.(S)*
